dbSNP ではバージョンアップの際にrs numberの融合が頻繁に起きており、古いSNP numberが最新版では消えているという悲しい現象がある。
今回、rs number融合の歴史（アーカイブ）をやっと見つけたので、紹介する。
[Offical Information]
- The dbSNP Mapping Process - SNP FAQ Archive - NCBI Bookshelf
Can’t you inform users when refSNP numbers have changed?
[Stats]
最新のdbSNP137に至るまでの、バージョンアップ時のSNP融合数を示す。
Number of merged RefSNPs.
dbSNP
version
|
RefSNP cluster (rs#'s)
|
RefSNP cluster (validated)
|
Number of
merged RefSNPs
|
Genome
Build
|
Date available
|
125
|
10,430,753
|
4,868,126
|
-
|
GRCh35.1
|
2005/9/29
|
126
|
11,961,761
|
5,646,244
|
618,073
|
hg18?
|
2006/5/18
|
127
|
11,811,594
|
5,689,286
|
324,938
|
hg18?
|
2007/3/8
|
128
|
11,883,685
|
6,262,709
|
48,912
|
hg18?
|
2007/10/25
|
129
|
14,708,752
|
6,573,789
|
1,823
|
hg18?
|
2008/4/14
|
130
|
17,804,034
|
6,573,584
|
4,639,885
|
GRCh36.3/hg18
|
2009/4/30
|
131
|
23,653,737
|
14,653,228
|
194,771
|
GRCh37.1/hg19
|
2010/3/25
|
132
|
30,442,771
|
19,727,605
|
224,198
|
GRCh37.1/hg19
|
2010/9/23
|
133
|
-
|
-
|
10,964
|
-
|
2011/1/31
|
134
|
41,365,915
|
6,961,883
|
1,632
|
GRCh37.2/hg19
|
2011/8/8
|
135
|
52,327,221
|
41,740,143
|
616,973
|
GRCh37.3/hg19
|
2011/10/13
|
136
|
-
|
-
|
63,345
|
-
|
to be determined
|
137
|
53,558,214
|
38,077,993
|
1,494,661
|
GRCh37.3/hg19
|
2012/6/26
|
[Links]
- The Current State of dbSNP
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